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Toluca vs Santos Laguna Prediction - 21 September 2026

Liga MXMexicoFull time
Toluca
2-3
Santos Laguna

Our pick:Home win

Odds 1.30Lost

74%
Correct score
2-0
Alternative
3-0
Wins
5/5Toluca · last 5 games

Bookmaker odds

1Home
1.20
XDraw
6.55
2Away
10.50
More markets
Total goals
Over 1.51.04
Under 1.56.80
Over 2.51.27
Under 2.53.14
Over 3.51.80
Under 3.51.93
Both teams to score
Yes1.67
No2.08
Odd/Even
Odd1.85
Even1.85
Handicap
Home -21.94
Away +21.78

Form

Toluca
  1. W 1-0
  2. W 5-2
  3. W 2-0
  4. W 2-0
  5. W 4-0
Santos Laguna
  1. W 2-1
  2. L 0-1
  3. D 0-0
  4. L 2-3
  5. L 0-1

Head to head

  1. 15 Jan 2026 Toluca 3 Santos Laguna 1 Liga MX
  2. 17 Jul 2025 Santos Laguna 2 Toluca 4 Liga MX
Prediction, preview and head to head: Toluca vs Santos Laguna

Match analysis

Toluca have scored 14 goals and conceded just two across their last five Liga MX matches, a run that dwarfs anything Santos Laguna have managed away from home this month. Superior is backing that gap to hold with the home win in Toluca vs Santos Laguna on 21 September, priced at 1.30 with the model's confidence at 74 percent.

Toluca have scored 14 and conceded two in five matches

The run reads five straight wins: 1-0 away at Puebla, then home routs of Atlas (5-2), Monterrey (2-0), Leon (2-0) and FC Juarez (4-0). That puts Toluca's scoring average at 2.8 goals a game against Santos Laguna's 0.8, and the head to head backs the same story. Toluca have won the last three meetings between these two, 3-1, 4-2 away and 2-1, so recent history and current form point the same direction.

Santos Laguna's only win in five came on the road

Santos Laguna's five match log is one win, one draw and three losses, and that win was a 2-1 scoreline away at FC Juarez, the exact shape of result that would beat Toluca tonight. A draw needs Toluca to go scoreless for the first time in five games, and an away win needs Santos Laguna to repeat a performance they have not managed at home in three attempts this month.

Formations

Confirmed formations

Toluca: 4-2-3-1(confirmed lineup)Santos Laguna: 4-2-3-1(confirmed lineup)

Today's acca

2 matches, total odds 1.50
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